TY - JOUR PY - 2007// TI - Fatal outcome in a child after ingestion of a transdermal fentanyl patch JO - International journal of legal medicine A1 - Teske, Jorg A1 - Weller, Jens-Peter A1 - Larsch, Klaus A1 - Troger, Hans Dieter A1 - Karst, Matthias SP - 147 EP - 151 VL - 121 IS - 2 N2 - The case history and toxicological findings of a fatal fentanyl intoxication due to ingestion of a transdermal patch are presented. A 1-year-old otherwise healthy girl was put to bed and 2 h later she was found dead. The autopsy revealed a 25-microg/h (4.2 mg) transdermal fentanyl patch in the stomach. Toxicological analysis by liquid chromatography-tandem mass spectrometry with positive electrospray ionization yielded fentanyl and norfentanyl concentrations in the peripheral blood of 5.6 and 5.9 ng/ml, heart blood 19.0 and 8.9 ng/ml, and liver 235 and 26 ng/g, respectively. The cause of death was determined to be a fentanyl overdose. The investigation established that the child has unintentionally swallowed the patch, which had been lying on the floor.

Language: en

LA - en SN - 0937-9827 UR - http://dx.doi.org/10.1007/s00414-006-0137-3 ID - ref1 ER -