TY  - JOUR
PY  - 2006//
TI  - Risk factors for completed suicide in schizophrenia and other chronic psychotic disorders: a case-control study
JO  - Schizophrenia Research
A1  - McGirr, Alexandre
A1  - Tousignant, Michel
A1  - Routhier, Don
A1  - Pouliot, L.
A1  - Chawky, Nadia
A1  - Margolese, Howard C.
A1  - Turecki, Gustavo
SP  - 132
EP  - 143
VL  - 84
IS  - 1
N2  - OBJECTIVE: Despite an increased risk for suicide among individuals diagnosed with psychotic disorders, risk factors for completed suicide remain largely unexamined in this population. Using a case-control design, this study aimed to investigate clinical and behavioural risk factors for suicide completion in schizophrenia and other chronic psychotic disorders. METHOD: A total of 81 psychotic subjects were examined; of these, 45 died by suicide. Proxy-based interviews with, on average, 2 informants were conducted using the SCID I and II interviews and a series of personality trait assessments. RESULTS: Psychotic individuals at risk for suicide are most readily identified by the presence of depressive disorders NOS, moderate to severe psychotic symptoms and a family history of suicidal behaviour. They also exhibited fewer negative symptoms, had more comorbid diagnoses and, contrary to findings in other populations, we found that cluster A and C personality trait symptoms seem to have protective effects against suicide in schizophrenics and other chronic psychotic suicides. CONCLUSIONS: Our study suggests that behavioural mediators of suicide risk, such as impulsive-aggressive behaviours, do not play a role in schizophrenic and chronic psychotic suicide. This is contrary to findings in other diagnostic groups, thus implying heterogeneity in predisposing mechanisms involved in suicide.<p />  <p>Language: en</p>
LA  - en
SN  - 0920-9964
UR  - http://dx.doi.org/10.1016/j.schres.2006.02.025
ID  - ref1
ER  -