TY - JOUR PY - 2006// TI - Childhood sexual abuse in relation to neurobiological challenge tests in patients with borderline personality disorder and normal controls JO - Psychiatry research A1 - Zweig-Frank, H. A1 - Paris, J. A1 - Ng Ying Kin, Ng Mien Kwong A1 - Schwartz, G. A1 - Steiger, H. A1 - Vasavan Nair, N. P. SP - 337 EP - 341 VL - 141 IS - 3 N2 - This study examined whether abnormal responses to neurobiological challenge tests in borderline personality disorder (BPD) are related to a history of childhood sexual abuse (CSA). We compared patients meeting BPD criteria (n=24), with and without histories of CSA, with normal controls (n=12) on the results of challenges with meta-chlorphenylpiperazine (m-CPP), pyridostigmine and clonidine. No differences were found between abused and non-abused patients with BPD. These results do not support the hypothesis that CSA is directly related to neurobiological abnormalities in BPD.
Language: en
LA - en SN - 0165-1781 UR - http://dx.doi.org/10.1016/j.psychres.2005.02.009 ID - ref1 ER -