TY - JOUR PY - 2006// TI - Genetic and environmental contributions to common psychopathologies of childhood and adolescence: a study of twins and their siblings JO - Journal of abnormal child psychology A1 - Ehringer, Marissa A. A1 - Rhee, Soo Hyun A1 - Young, S. A1 - Corley, Robin A1 - Hewitt, J. K. SP - 1 EP - 17 VL - 34 IS - 1 N2 - We report findings based on analyses of self-reports of six common adolescent psychopathologies (attention deficit/hyperactivity disorder, ADHD; conduct disorder, CD; oppositional defiant disorder, ODD; generalized anxiety disorder, GAD; separation anxiety disorder, SAD; and major depressive disorder, MDD) in a sample of 1,162 male and female adolescent (12-19 years) twin pairs and 426 siblings. Prevalence statistics for past year and lifetime reports confirm differences between genders for CD, GAD, SAD, and MDD, and a lack of differences between twins and their non-twin siblings. Biometrical modeling was conducted to ascertain the relative influences of genes, and shared and non-shared environments contributing to these disorders. A more robust estimate of these parameters was obtained by including non-twin siblings. Age-specific thresholds were integrated into the analyses to appropriately model the developmental patterns of behavior. We found evidence for both genetic and non-shared environmental influences for all disorders. Shared environmental influences also seem to be important for MDD and lifetime GAD.
Language: en
LA - en SN - 0091-0627 UR - http://dx.doi.org/10.1007/s10802-005-9000-0 ID - ref1 ER -