TY - JOUR PY - 2006// TI - Smaller volume of anterior cingulate cortex in abuse-related posttraumatic stress disorder JO - Journal of affective disorders A1 - Kitayama, Noriyuki A1 - Quinn, S. A1 - Bremner, J. Douglas SP - 171 EP - 174 VL - 90 IS - 2-3 N2 - OBJECTIVE: The anterior cingulate cortex (ACC) plays an important role in emotion, and studies in animals have shown changes in ACC structure with early life stress. The purpose of this study was to measure volume of the ACC in PTSD. METHOD: Magnetic resonance imaging (MRI) was used to measure ACC volume in 8 subjects with abuse-related PTSD and 13 healthy subjects without PTSD. ACC volume included Brodmann's area BA 24 and 32. RESULTS: Right ACC volume in PTSD patients was significantly smaller than in non-PTSD subjects. CONCLUSION: These results are consistent with smaller ACC volume in PTSD.
Language: en
LA - en SN - 0165-0327 UR - http://dx.doi.org/10.1016/j.jad.2005.11.006 ID - ref1 ER -