TY  - JOUR
PY  - 1976//
TI  - Heritable factors in the severity of affective illness
JO  - Biological psychiatry
A1  - Dunner, D. L.
A1  - Gershon, Elliot S.
A1  - Goodwin, Frederick K.
SP  - 31
EP  - 42
VL  - 11
IS  - 1
N2  - A review of clinical experience with 163 patients with primary affective disorder indicates that patients with a history characterized by recurrent depression interspersed with periods of hypomania (bipolar II) may have clinical courses that are distinguishable from bipolar I (depression with histories of mania) or unipolar patients. A prior history of suicide attempt and suicide after discharge from the research unit were most frequent among bipolar II patients. The family histories of bipolar I and bipolar II patients revealed similarly increased morbid risks for bipolar illness, whereas no bipolar illness was found in the first-degree relatives of unipolar patients. The suggestion that patients classified as bipolar II be separately considered in future studies of affective disorder is discussed.<p /> <p>Language: en</p> 
LA  - en
SN  - 0006-3223
UR  - http://dx.doi.org/
ID  - ref1
ER  -