TY  - JOUR
PY  - 1978//
TI  - Clinical pharmacology and toxicology of antidepressants
JO  - Hospital practice
A1  - Biggs, J. T.
SP  - 79
EP  - 84
VL  - 13
IS  - 2
N2  - Described as the drugs of choice in treating acute depression, the tricyclics are unusual in that too high a dosage may be as ineffective as one that is too low, and plasma levels may vary as much as 30-fold among patients given the same dosage. After the recommended approach to determining appropriate dosage has been tried, the 15% or so of patients who do not respond are not likely to benefit from a switch of drugs.<p /> <p>Language: en</p> 
LA  - en
SN  - 0018-5809
UR  - http://dx.doi.org/
ID  - ref1
ER  -