TY  - JOUR
PY  - 1980//
TI  - Toxicity of alkaline solutions
JO  - Annals of emergency medicine
A1  - Vancura, E. M.
A1  - Clinton, Joseph E.
A1  - Ruiz, E.
A1  - Krenzelok, Edward P.
SP  - 118
EP  - 122
VL  - 9
IS  - 3
N2  - We examined the question of what determines the toxicity of alkaline solutions--pH, viscosity, or other factors. Our experiments have identified pH measurement as the simplest and most easily measured parameter for determining initial management of caustic ingestions. Viscosity is not a clinically useful measurement. The closer to 14 the pH measures, the more destructive the caustic. Non-lye solutions known to cause esophageal ulceration have a pH of 12.5 to 13.5. Most cases of deep ulceration going on to stricture formation involve lye solutions of pH 14. The critical pH that causes esophageal ulceration is 12.5, and thus a patient ingesting a substance with a pH greater than 12 should be followed closely for the possibility of esophageal ulceration.<p /> <p>Language: en</p> 
LA  - en
SN  - 0196-0644
UR  - http://dx.doi.org/
ID  - ref1
ER  -