TY - JOUR PY - 1982// TI - Podophyllum toxicity: a report of a fatal case and a review of the literature JO - Journal of toxicology - clinical toxicology A1 - Cassidy, D. E. A1 - Drewry, J. A1 - Fanning, J. P. SP - 35 EP - 44 VL - 19 IS - 1 N2 - A 59-yr-old male ingested 10 g of podophyllum in a fatal suicide attempt. Previously unreported nuclear and cytoplasmic changes were observed in circulating leukocytes. Symptoms did not occur until 10 h after ingestion with loss of reflexes, coma, and a marked lactic acidosis. Despite hemoperfusion, the patient expired 39 h after ingestion. The literature on podophyllum toxicity is reviewed.

Language: en

LA - en SN - 0731-3810 UR - http://dx.doi.org/ ID - ref1 ER -