TY  - JOUR
PY  - 1985//
TI  - Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan
JO  - Neuropsychobiology
A1  - López-Ibor, J. J. Jr
A1  - Saiz-Ruiz, Jeronimo
A1  - Pérez de los Cobos, J. C.
SP  - 67
EP  - 74
VL  - 14
IS  - 2
N2  - 5-Hydroxyindoleacetic acid (5-HIAA) and cortisol in cerebrospinal fluid (CSF), response of the dexamethasone suppression test (DST) and the clinical response to treatment with 5-hydroxytryptophan (5-HTp) plus carbidopa were studied in a group of 21 depressed inpatients (major depression with melancholia) in order to correlate biological findings with psychopathologicalones. A positive correlation was found between strong suicidal thoughts, suicidal attempts and self-aggressivity and low concentration of 5-HIAA in CSF and a less significant but still positive correlation with abnormal DST response and with clinical response to the treatment.<p /> <p>Language: en</p> 
LA  - en
SN  - 0302-282X
UR  - http://dx.doi.org/
ID  - ref1
ER  -