TY  - JOUR
PY  - 1988//
TI  - A case of sotalol poisoning with fatal outcome
JO  - Journal of toxicology - clinical toxicology
A1  - Perrot, D.
A1  - Bui-Xuan, B.
A1  - Lang, Johannes
A1  - Bouffard, Y.
A1  - Delafosse, B.
A1  - Faucon, G.
A1  - Motin, J.
SP  - 389
EP  - 396
VL  - 26
IS  - 5-6
N2  - The case of a 58 year old woman who died after ingestion of 14.4 g of sotalol and 50 mg of triazolam is described. Despite medical treatment, intracardiac pacing and hemodialysis, cardiovascular failure persisted and became irreversible. High sotalol concentrations were observed in plasma (65 micrograms/ml) and in post mortem tissues samples. Tissue to plasma ratios ranged from 2.5 to 6. The high drug concentration found in heart tissue (104.4 micrograms/g) explains the difficulties experienced in the sotalol poisoning.<p />  <p>Language: en</p>
LA  - en
SN  - 0731-3810
UR  - http://dx.doi.org/
ID  - ref1
ER  -