TY - JOUR PY - 1989// TI - 3H-imipramine binding in the frontal cortex of suicides JO - Psychiatry research A1 - Arora, R. C. A1 - Meltzer, Herbert Y. SP - 125 EP - 135 VL - 30 IS - 2 N2 - Imipramine binding (desipramine- and serotonin-sensitive) was determined in the frontal cortex of suicide victims and nonpsychiatric controls who died due to medical disease or accidents. There were no differences in Kd or Bmax of imipramine binding between controls and suicides. The Kd and Bmax values of serotonin-sensitive imipramine binding were significantly lower than desipramine-sensitive imipramine binding, both in controls and suicides. There were significant correlations between Kd and Bmax of serotonin-sensitive imipramine binding and desipramine-sensitive imipramine binding in suicides but not in controls.

Language: en

LA - en SN - 0165-1781 UR - http://dx.doi.org/ ID - ref1 ER -