TY - JOUR PY - 1991// TI - The low affinity component of 3H.clonidine binding is absent in the prefrontal cortex of presumptive suicide victims JO - Brain research A1 - Andorn, A. C. SP - 276 EP - 278 VL - 568 IS - 1-2 N2 - Dysfunction in alpha-adrenergic receptor systems has been implicated to be of etiologic significance in depressive illness. The alpha 2-adrenergic ligand 3H.clonidine labels at least two sets of binding sites in normal human prefrontal cortex. We now report that the lower affinity component of 3H.clonidine binding is apparently absent in the prefrontal cortices of presumptive suicide victims.

Language: en

LA - en SN - 0006-8993 UR - http://dx.doi.org/ ID - ref1 ER -