TY - JOUR PY - 1992// TI - Bupropion and alcohol fatal intoxication: case report JO - Forensic science international A1 - Ramcharitar, V. A1 - Levine, B. S. A1 - Goldberger, Bruce A. A1 - Caplan, Y. H. SP - 151 EP - 156 VL - 56 IS - 2 N2 - A fatality due to the ingestion of bupropion and ethanol is presented. Bupropion and its metabolites were extracted from several tissues and identified using gas chromatography with nitrogenphosphorus and mass spectrometry detection. The concentrations of bupropion, hydroxybupropion and the erythroamino and threoamino alcohol metabolites in heart blood were 4.2, 5.0, 0.6 and 4.6 mg/l, respectively. The heart blood ethanol concentration was 0.27 g/dl. In addition, bupropion was distributed as follows: subclavian blood, 6.2 mg/l; bile, 1.4 mg/l; kidney, 2.4 mg/l; liver, 1.0 mg/kg; stomach contents, 16 mg and urine, 37 mg/l.
Language: en
LA - en SN - 0379-0738 UR - http://dx.doi.org/ ID - ref1 ER -