TY - JOUR PY - 1992// TI - Modulatory role of serotonin in neural information processing: implications for human psychopathology JO - Psychological bulletin A1 - Spoont, Michele R. SP - 330 EP - 350 VL - 112 IS - 2 N2 - Investigation of the role of 5-hydroxytryptophan (5-HT), which functions as a modulator in the central nervous system, across behavioral contexts suggests that a general principle of transmitter function may be derived that is independent of specific behaviors and specific neural loci. A functional principle of 5-HT action in neural information processing in the central nervous system is proposed. Extremes deviations in 5-HT activity result in biases in information processing that may have direct effects on behavior. Such biases may predispose to pathological conditions such as violent suicide and aggression.
Language: en
LA - en SN - 0033-2909 UR - http://dx.doi.org/ ID - ref1 ER -