TY  - JOUR
PY  - 2009//
TI  - Neural correlates of value, risk, and risk aversion contributing to decision making under risk
JO  - Journal of neuroscience
A1  - Christopoulos, George I.
A1  - Tobler, Philippe N.
A1  - Bossaerts, Peter
A1  - Dolan, Raymond J.
A1  - Schultz, Wolfram
SP  - 12574
EP  - 12583
VL  - 29
IS  - 40
N2  - Decision making under risk is central to human behavior. Economic decision theory suggests that value, risk, and risk aversion influence choice behavior. Although previous studies identified neural correlates of decision parameters, the contribution of these correlates to actual choices is unknown. In two different experiments, participants chose between risky and safe options. We identified discrete blood oxygen level-dependent (BOLD) correlates of value and risk in the ventral striatum and anterior cingulate, respectively. Notably, increasing inferior frontal gyrus activity to low risk and safe options correlated with higher risk aversion. Importantly, the combination of these BOLD responses effectively decoded the behavioral choice. Striatal value and cingulate risk responses increased the probability of a risky choice, whereas inferior frontal gyrus responses showed the inverse relationship. These findings suggest that the BOLD correlates of decision factors are appropriate for an ideal observer to detect behavioral choices. More generally, these biological data contribute to the validity of the theoretical decision parameters for actual decisions under risk.<p />  <p>Language: en</p>
LA  - en
SN  - 0270-6474
UR  - http://dx.doi.org/10.1523/JNEUROSCI.2614-09.2009
ID  - ref1
ER  -