TY  - JOUR
PY  - 1993//
TI  - Anogenital warts in children
JO  - Clinical and experimental dermatology
A1  - Handley, J. M.
A1  - Maw, R. D.
A1  - Bingham, E. A.
A1  - Horner, T.
A1  - Bharucha, H.
A1  - Swann, A.
A1  - Lawther, H.
A1  - Dinsmore, W. W.
SP  - 241
EP  - 247
VL  - 18
IS  - 3
N2  - Fourteen children presenting with anogenital (AG) warts and their close family members were studied; 28.6 and 8.3% of presenting children and other child household members, respectively, had non-genital cutaneous warts; 42.8% of children with AG warts had one or more adult household member with common hand warts. Fifty per cent of all mothers had subclinical cervical papilloma virus (PV) infection; only one male adult had subclinical PV infection of the penis without concurrent AG warts. Of the children with AG warts 42.8% had one or more adult household member with AG warts. Human papilloma virus (HPV) deoxyribonucleic acid (DNA), type 6/11 most frequently, was detected in 38.5% AG wart biopsies from children, and 67% AG wart biopsies from adults. HPV 31/33/35 was detected in 28.5% of cervical preneoplasias and type 6/11 in the one case of subclinical PV infection of the penile shaft. Detection of HPV types 6/11, 16/18, or 31/33/35 in AG warts in children was significantly associated with vertical (from an HPV-infected maternal birth canal during vaginal delivery) or sexual transmission of these warts (Fisher exact probability P = 0.031).<p />  <p>Language: en</p>
LA  - en
SN  - 0307-6938
UR  - http://dx.doi.org/
ID  - ref1
ER  -