TY - JOUR PY - 1988// TI - Acute poisoning with a narcotic (Tramadol) in an infant of five weeks JO - Helvetica Paediatrica Acta A1 - Bianchetti, M. G. A1 - Beutler, A. A1 - Ferrier, P. E. SP - 241 EP - 244 VL - 43 IS - 3 N2 - Accidental rectal administration of 27 mg/kg of the narcotic analgesic Tramadol to a five-week-old infant resulted in severe cerebral depression, which had to be treated with Naloxone during 48 hours. The severity and the duration of this intoxication are not explained solely by the high dosage of Tramadol. A decreased elimination kinetics and an increased permeability of the blood-cerebrospinal fluid barrier probably also account for the pattern of the present intoxication.

Language: fr

LA - fr SN - 0018-022X UR - http://dx.doi.org/ ID - ref1 ER -