TY - JOUR PY - 2010// TI - Drinking and future thinking: acute effects of alcohol on prospective memory and future simulation JO - Psychopharmacology A1 - Paraskevaides, Theadora A1 - Morgan, C. J. A. A1 - Leitz, Julie R. A1 - Bisby, James A. A1 - Rendell, Peter G. A1 - Curran, H. Valerie SP - 301 EP - 308 VL - 208 IS - 2 N2 - BACKGROUND: It has recently been shown that acute alcohol globally impairs 'prospective memory' (PM)-remembering to do something in the future (Leitz et al. in Psychopharmacology 205:379-387, 2009). In healthy, sober individuals, simulating future events at encoding enhances PM performance. AIMS: We therefore aimed to determine if future event simulation could attenuate the impairing effects of acute alcohol on PM. METHODS: Using a double-blind independent group design, 32 healthy volunteers were administered a 0.6-g/kg dose of ethanol or matched placebo. PM performance was assessed using a behavioural task, the 'Virtual Week', which was adapted to enable future event simulation in both remote and recent contexts. Episodic memory was indexed with a source memory task and planning with the Tower of London task. RESULTS: We replicated the finding of Leitz et al. that acute alcohol consumption impairs prospective memory for event-based tasks. Future event simulation significantly improved PM performance on these tasks and eliminated the PM deficit caused by acute alcohol consumption. CONCLUSIONS: This is the first evidence that future event simulation can overcome alcohol-induced deficits in prospective memory and may have important clinical implications for the rehabilitation of chronic alcohol users.
Language: en
LA - en SN - 0033-3158 UR - http://dx.doi.org/10.1007/s00213-009-1731-0 ID - ref1 ER -