TY  - JOUR
PY  - 2009//
TI  - Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors,
JO  - Nature
A1  - Seal, Rebecca P.
A1  - Wang, Xingmei
A1  - Guan, Yabo
A1  - Raja, Srinivasa N.
A1  - Woodbury, C. Jeffery
A1  - Basbaum, Allan I.
A1  - Edwards, Robert H.
SP  - 651
EP  - 655
VL  - 462
IS  - 7273
N2  - Despite the contribution of mechanical pain to the morbidity associated with inflammation and trauma, the primary sensory neurons that convey this sensation have not been identified. Using knockout mice, the loss of the low abundance vesicular glutamate transporter VGLUT3, expressed by a small subset of peripheral sensory neurons projecting to areas implicated in persistent pain caused by injury, is now shown to specifically impair mechanical pain sensation.<p />
LA  - 
SN  - 0028-0836
UR  - http://dx.doi.org/10.1038/nature08505
ID  - ref1
ER  -