TY - JOUR PY - 2010// TI - Causes of aggressive behavior in patients with dementia JO - Journal of clinical psychiatry A1 - Kunik, M. E. A1 - Snow, A. Lynn A1 - Davila, Jessica A. A1 - Steele, Avila B. A1 - Balasubramanyam, Valli A1 - Doody, Rachelle S. A1 - Schulz, Paul E. A1 - Kalavar, Jagadeesh S. A1 - Morgan, Robert O. SP - 1145 EP - 1152 VL - 71 IS - 9 N2 - OBJECTIVE: To examine factors predicting development of aggression. METHOD: Community-dwelling patients over 60 years of age in a Veterans Affairs Medical Center who had a documented ICD-9-CM code for dementia within 12 months of screening and no other dementia codes recorded for 2 preceding years but no aggressive behavior during the 12 months preceding study initiation were assessed every 4 months for 24 months for aggression, depression, pain, patient/caregiver relationship quality (mutuality), involvement in pleasant events, and caregiver burden. The study was conducted from September 5, 2003, to June 10, 2005. RESULTS: Of 215 patients, 89 (41%) developed aggression. In individual models, high baseline mutuality decreased risk of aggression; high burden and pain increased risk. Increases in depression and pain and declines in total mutuality also increased risk. In a full model and step-wise model, high levels of baseline caregiver burden, worst pain, and decline in mutuality over time increased risk of aggression. CONCLUSIONS: Many dementia patients become aggressive. Higher levels of worst pain, caregiver burden, and declining mutuality over time increase risk of aggression.
Language: en
LA - en SN - 0160-6689 UR - http://dx.doi.org/10.4088/JCP.08m04703oli ID - ref1 ER -