TY  - JOUR
PY  - 2010//
TI  - A preliminary investigation of motor evoked potential abnormalities following sport-related concussion
JO  - Brain injury
A1  - Livingston, Scott C.
A1  - Saliba, Ethan N.
A1  - Goodkin, Howard P.
A1  - Barth, Jeffrey T.
A1  - Hertel, Jay N.
A1  - Ingersoll, C. D.
SP  - 904
EP  - 913
VL  - 24
IS  - 6
N2  - Background: Assessment of concussion is primarily based on self-reported symptoms, neurological examination and neuropsychological testing. The neurophysiologic sequelae and the integrity of the corticomotor pathways could be obtained by evaluating motor evoked potentials (MEPs). Objectives: To compare MEPs obtained through transcranial magnetic stimulation (TMS) in acutely concussed and non-concussed collegiate athletes. Methods: Eighteen collegiate athletes (12 males, six females, aged 20.4 +/- 1.3 years) including nine subjects with acute concussion (</=24 hours) matched to nine control subjects. TMS was applied over the motor cortex and MEP responses were recorded from the contralateral upper extremity. MEP thresholds (%), latencies (milliseconds per metre) and amplitudes were assessed. Central motor conduction time (CMCT) was calculated from MEP, M response and F wave latencies. Testing was performed on days 1, 3, 5 and 10 post-concussion. Results: Ulnar MEP amplitudes were significantly different between post-concussion days 3 and 5 (F(3,48) = 3.13, p = 0.041) with smaller amplitudes recorded on day 3 (0.28 +/- 0.10 ms m(-1)). Median MEP latencies were significantly longer (F(3,48) = 4.53, p = 0.023) 10 days post-concussion (27.1 +/- 1.4 ms m(-1)) compared to day 1 (25.7 +/- 1.5 ms m(-1)). No significant differences for motor thresholds or CMCTs were observed (p > 0.05). Conclusion: MEP abnormalities among acutely concussed collegiate athletes provide direct electrophysiologic evidence for the immediate effects of concussion.<p />  <p>Language: en</p>
LA  - en
SN  - 0269-9052
UR  - http://dx.doi.org/10.3109/02699051003789245
ID  - ref1
ER  -