TY - JOUR PY - 2011// TI - Neuropsychiatric Disorders in Persons With Severe Traumatic Brain Injury: Prevalence, Phenomenology, and Relationship With Demographic Clinical and Functional Features JO - Journal of head trauma rehabilitation A1 - Ciurli, Paola A1 - Formisano, Rita A1 - Bivona, Umberto A1 - Cantagallo, Anna A1 - Angelelli, Paola SP - 116 EP - 126 VL - 26 IS - 2 N2 - OBJECTIVE: This study aimed to characterize neuropsychiatric symptoms in a large group of individuals with severe traumatic brain injury (TBI) and to correlate these symptoms with demographic, clinical, and functional features. METHODS: The Neuropsychiatric Inventory (NPI), a frequently used scale to assess behavioral, emotional, and motivational disorders in persons with neurological diseases, was administered to a sample of 120 persons with severe TBI. Controls were 77 healthy subjects. RESULTS: A wide range of neuropsychiatric symptoms was found in the population with severe TBI: apathy (42%), irritability (37%), dysphoria/depressed mood (29%), disinhibition (28%), eating disturbances (27%), and agitation (24%). A clear relationship was also found with other demographic and clinical variables. CONCLUSION: Neuropsychiatric disorders constitute an important part of the comorbidity in populations with severe TBI. Our study emphasizes the importance of integrating an overall assessment of cognitive disturbances with a specific neuropsychiatric evaluation to improve clinical understanding and treatment of persons with TBI.
Language: en
LA - en SN - 0885-9701 UR - http://dx.doi.org/10.1097/HTR.0b013e3181dedd0e ID - ref1 ER -