TY - JOUR PY - 2010// TI - Suicide by hanging under the influence of ketamine and ethanol JO - Forensic science international A1 - Dinis-Oliveira, Ricardo Jorge A1 - Carvalho, Felix A1 - Duarte, Jose Alberto A1 - Dias, Ricardo A1 - Magalhães, Teresa A1 - Santos, Agostinho SP - e23 EP - 7 VL - 202 IS - 1-3 N2 - Psychiatric deviations resulting from alcohol and illegal drug abuse may be considered a major risk factor for suicidal behavior. This report describes a suicide by hanging, under the influence of ketamine and alcohol. The victim was a 29-year-old man, found dead hanging by the neck from a metallic beam in the ceiling of his workplace. Besides characteristic signs of hanging seen at the autopsy, toxicological analysis revealed a femoral blood concentration of ketamine and ethanol of 1.3mg/L and 0.66g/L, respectively. Positive qualitative results for ketamine were also detected, in a powder found near the victim and on the victim's nostrils, which suggests nasal inhaling as administration route. The hallucinogenic effects caused by ketamine, associated with an increased sensitivity of N-methyl-d-aspartate (NMDA) receptors to ketamine as result of the previous history of alcoholism should be considered as potential inducing factors in suicide behaviors.
Language: en
LA - en SN - 0379-0738 UR - http://dx.doi.org/10.1016/j.forsciint.2010.04.047 ID - ref1 ER -