TY - JOUR PY - 1993// TI - Acute toxicity of zidovudine. Analysis of the literature and number of cases at the Paris Poison Control Center JO - Therapie A1 - Maignen, F. A1 - Meglio, S. A1 - Bidault, I. A1 - Castot, A. SP - 129 EP - 131 VL - 48 IS - 2 N2 - 13 cases of zidovudine overdosage have been previously published; 30 have been notified to Paris Control Poison Centre up to January 1991. This analysis shows that acute toxicity appears infrequent and mild when ingested dose is lower than 25 gr. However it appears from this series that an haematologic monitoring is needed because of the risk of myelosuppression.

Language: fr

LA - fr SN - 0040-5957 UR - http://dx.doi.org/ ID - ref1 ER -