TY  - JOUR
PY  - 2010//
TI  - Clinical significance of unsuspected rise in cardiac troponin in the setting of falls in older people
JO  - Emergency medicine journal
A1  - Maréchaux, Sylvestre
A1  - Lubret, Remy
A1  - Delsart, Pascal
A1  - Hattabi, Medhi
A1  - Six-Carpentier, Marie-Michele
A1  - Carpentier, Emilie
A1  - Coutant, Veronique
A1  - Pinçon, Claire
A1  - Le Tourneau, Thierry
A1  - Puisieux, Francois
A1  - Goldstein, Patrick
A1  - Asseman, Philippe
A1  - Ennezat, Pierre Vladimir
SP  - 446
EP  - 450
VL  - 27
IS  - 6
N2  - OBJECTIVES: To assess the clinical significance of unsuspected rise in cardiac troponin I (cTnI) levels in elderly patients who have fallen. DESIGN: Monocentre prospective observational pilot study. PARTICIPANTS: Consecutive elderly patients (age >65 years) referred to the emergency department after being immobilised on the ground after a fall. MEASUREMENTS: Clinical, laboratory and Doppler echocardiography data were collected on admission to assess the cardiac correlates of increased cTnI. The survival endpoint was a composite of death or cardiovascular event. RESULTS: 60 patients were included in this study. Mean age was 81+/-8 years. Cardiac TnI was > or =0.05 ng/ml in at least one blood sample in 40 patients (67%). New diagnosis of cardiac disease was performed in 14 patients, 13 of them had cTnI > or =0.05 ng/ml. Transient apical ballooning was diagnosed in six patients. During a median follow-up of 92 (49-131) days death occurred in six patients, myocardial infarction in three, stroke in one and acute heart failure in five. Cardiac TnI > or =0.05 ng/ml was a predictor of these events (p=0.034). CONCLUSION: An unsuspected rise in cTnI correlates with new diagnosis of cardiac disease and is a potential marker of stress induced cardiomyopathy in elderly patients who fall. Cardiac TnI might be a strong predictor of outcome in these patients.<p />  <p>Language: en</p>
LA  - en
SN  - 1472-0205
UR  - http://dx.doi.org/10.1136/emj.2009.076406
ID  - ref1
ER  -