TY - JOUR PY - 1993// TI - Broad beans as a cause of acute hemolytic anemia JO - Deutsche Medizinische Wochenschrift A1 - Riepl, R. L. A1 - Schreiner, J. A1 - Muller, B. A1 - Hildemann, S. A1 - Loeschke, K. SP - 932 EP - 935 VL - 118 IS - 25 N2 - A previously healthy 17-year-old Greek boy suddenly developed jaundice of sclerae and skin. In addition, physical examination revealed a pale appearance. He also reported feeling tired and weak. The haemoglobin level was 9.6 g/dl, lactate dehydrogenase activity 335 U/l, bilirubin concentration 3.2 mg/dl (direct bilirubin 0.7 mg/dl, indirect bilirubin 2.5 mg/dl), haptoglobin concentration 48.8 mg/dl. As haemolytic anaemia was assumed, direct questioning elicited the fact that the patient had, for the first time in his life, eaten 300 g of broad beans (Vicia faba) on each of two days, namely 3 and 2 days before the appearance of jaundice. Absence of glucose-6-phosphate dehydrogenase activity in the red blood corpuscles confirmed the diagnosis of favism. On symptomatic treatment both the enzyme activities and the bilirubin level fell to normal within one week, and the haemoglobin level was 15.7 g/dl after 4 weeks.
Language: de
LA - de SN - 0012-0472 UR - http://dx.doi.org/10.1055/s-2008-1059408 ID - ref1 ER -