TY - JOUR PY - 1995// TI - Gabapentin toxicity in children manifesting as behavioral changes JO - Epilepsia A1 - Wolf, S. M. A1 - Shinnar, Shlomo A1 - Kang, Heejoon A1 - Gil, K. B. A1 - Moshé, S. L. SP - 1203 EP - 1205 VL - 36 IS - 12 N2 - Pediatric experience with gabapentin (GBP), a new antiepileptic drug (AED), is limited. We described 3 learning disabled children, 1 aged 7 and 2 aged 10 years, with intractable partial seizures who developed severe behavioral problems while receiving modest doses of GBP. The children became hyperactive and had explosive outburst consisting of aggressive and oppositional behavior. The behavioral problems were sufficiently severe to require discontinuation of GBP despite moderately improved seizure control.
Language: en
LA - en SN - 0013-9580 UR - http://dx.doi.org/ ID - ref1 ER -