TY  - JOUR
PY  - 1996//
TI  - Mechanisms and evaluation of multiple organ and system failure after trauma
JO  - Revista do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo
A1  - Fontes, Belchor
A1  - Poggetti, Renato Sérgio
SP  - 72
EP  - 77
VL  - 51
IS  - 2
N2  - Multiple organ failure (MOF) is a major cause of death of ICU trauma patients. Despite intensive clinical and experimental investigation, the exact physiopathology of this syndrome is unclear. Although diverse cellular and humoral mediators have been identified, their mechanistic role is still debated. In this article the authors discuss recent results of this investigation. They present recently published criteria for MOF quantification, and focus on the mechanisms and mediators of MOF syndrome, emphasizing the role of sepsis, the intestinal ischemia/reperfusion MOF model, the role of polymorphonuclear neutrophil, and the relationship between adult respiratory distress syndrome (ARDS) and the development of MOF syndrome.<p /> <p>Language: pt</p> 
LA  - pt
SN  - 0041-8781
UR  - http://dx.doi.org/
ID  - ref1
ER  -