TY - JOUR PY - 2011// TI - Disorders of glucose metabolism: post mortem analyses in forensic cases-part II JO - International journal of legal medicine A1 - Musshoff, F. A1 - Hess, C. A1 - Madea, Burkhard SP - 171 EP - 180 VL - 125 IS - 2 N2 - In continuation to part I, a literature review is presented concerning biochemical problems of forensic post mortem cases of unclear hyperglycaemia or hypoglycaemia. Clinical parameters for this purpose were recently reviewed. Particular attention was paid to the detection of diabetic ketoacidosis, of hyperosmolar coma, insulinoma, insulin-induced or oral diabetic-induced hypoglycaemia. The second part of the review discusses the analytes ketone bodies, synthetic insulins, human insulin, C-peptide, proinsulin and insulin antibodies. Special interest is given to post mortem matrices for those analytes to reference concentrations, stability data, analytic interferences and analytical procedures which should be used in toxicological laboratories willing to detect diabetic metabolism disorders after death.
Language: en
LA - en SN - 0937-9827 UR - http://dx.doi.org/10.1007/s00414-010-0510-0 ID - ref1 ER -