TY - JOUR PY - 2011// TI - An unusual mimicker of a sepsis outbreak: ergot intoxication JO - European journal of pediatrics A1 - Bas, Ahmet Yagmur A1 - Demirel, Nihal A1 - Soysal, Ahmet A1 - Arslan, Kahraman A1 - Dilmen, Ugur SP - 633 EP - 637 VL - 170 IS - 5 N2 - Methylergonovine (MEV) is a semi-synthetic ergot alkaloid used in the prevention and control of postpartum hemorrhage. This report describes 12 newborns born on the same day in a local country hospital in Turkey and developed sepsis-like symptoms and encephalopathy within the first 6 h of life due to accidental administration of MEV instead of vitamin K in the delivery room. The major features of MEV poisoning were lethargy (41.7%), seizure (75.0%), feeding intolerance (66.6%), hypoventilation (58.3%), irritability (25%), and peripheral circulatory abnormalities (58.3%). As a conclusion, clinical findings of ergot toxicity in newborns cannot be distinguished from infectious disease or neonatal encephalopathy.

Language: en

LA - en SN - 0340-6199 UR - http://dx.doi.org/10.1007/s00431-010-1336-y ID - ref1 ER -