TY  - JOUR
PY  - 2010//
TI  - Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys
JO  - British journal of psychiatry
A1  - Kessler, Ronald C.
A1  - McLaughlin, Katie A.
A1  - Green, Jennifer Greif
A1  - Gruber, Michael J.
A1  - Sampson, Nancy A.
A1  - Zaslavsky, Alan M.
A1  - Aguilar-Gaxiola, Sergio
A1  - Alhamzawi, Ali Obaid
A1  - Alonso, Jordi
A1  - Angermeyer, Matthias
A1  - Benjet, Corina
A1  - Bromet, Evelyn
A1  - Chatterji, Somnath
A1  - de Girolamo, Giovanni
A1  - Demyttenaere, Koen
A1  - Fayyad, John
A1  - Florescu, Silvia E.
A1  - Gal, Gilad
A1  - Gureje, Oye
A1  - Haro, Josep Maria
A1  - Hu, Chi-Yi
A1  - Karam, Elie G.
A1  - Kawakami, Norito
A1  - Lee, Sing
A1  - Lépine, Jean-Pierre
A1  - Ormel, Johan
A1  - Posada-Villa, Jose
A1  - Sagar, Rajesh
A1  - Tsang, Adley
A1  - Üstün, Bedirhan T.
A1  - Vassilev, Svetlozar
A1  - Viana, Maria Carmen
A1  - Williams, Daniel R.
SP  - 378
EP  - 385
VL  - 197
IS  - 5
N2  - BACKGROUND: Although significant associations of childhood adversities with adult mental disorders are widely documented, most studies focus on single childhood adversities predicting single disorders. AIMS: To examine joint associations of 12 childhood adversities with first onset of 20 DSM-IV disorders in World Mental Health (WMH) Surveys in 21 countries. METHOD: Nationally or regionally representative surveys of 51 945 adults assessed childhood adversities and lifetime DSM-IV disorders with the WHO Composite International Diagnostic Interview (CIDI). RESULTS: Childhood adversities were highly prevalent and interrelated. Childhood adversities associated with maladaptive family functioning (e.g. parental mental illness, child abuse, neglect) were the strongest predictors of disorders. Co-occurring childhood adversities associated with maladaptive family functioning had significant subadditive predictive associations and little specificity across disorders. Childhood adversities account for 29.8% of all disorders across countries. CONCLUSIONS: Childhood adversities have strong associations with all classes of disorders at all life-course stages in all groups of WMH countries. Long-term associations imply the existence of as-yet undetermined mediators.<p />  <p>Language: en</p>
LA  - en
SN  - 0007-1250
UR  - http://dx.doi.org/10.1192/bjp.bp.110.080499
ID  - ref1
ER  -