TY - JOUR PY - 2011// TI - Screening for illicit drugs on Euro banknotes by LC-MS/MS JO - Forensic science international A1 - Wimmer, Kurt A1 - Schneider, Serge SP - 172 EP - 177 VL - 206 IS - 1-3 N2 - A method for the simultaneous quantification of illicit drugs on Euro banknotes, using an ultra-performance liquid chromatography tandem mass spectrometry, was developed and validated. The method included cocaine, benzoylecgonine, MDMA, MDEA, MDA, methamphetamine, diacetylmorphine, 6-MAM, morphine and Delta(9)-THC. Drug residues were monitored and quantified via positive ESI mode using multiple reaction monitoring. Banknotes were extracted with methanol by vigorous shaking. Recovery rates were in the range of 60-80%. Calibration was performed with spiked banknotes in the range of 10-100ng/note (R(2) 0.98-0.99). Intra-day analysis showed fair precision and accuracy (=15%). Matrix effects were in the range from 27% to 235%. 7-15 samples of each denomination were analyzed. The calculated median values per note were 106ng cocaine, 43ng benzoylecgonine, 41ng heroin, 15.5ng 6-MAM, 16.5ng morphine, 9ng MDMA and 7ng methamphetamine. Delta(9)-THC was detected on 4 banknotes. MDEA and MDA were not detected on any note. A widespread background contamination for cocaine and opiates was demonstrated.
Language: en
LA - en SN - 0379-0738 UR - http://dx.doi.org/10.1016/j.forsciint.2010.07.037 ID - ref1 ER -