TY - JOUR PY - 2006// TI - Studying alcohol elimination using the alcohol clamp method JO - Alcohol research and health A1 - Ramchandani, Vijay A. A1 - O'Connor, Sean SP - 286 EP - 290 VL - 29 IS - 4 N2 - Researchers studying alcohol absorption and metabolism in humans have been aided by the alcohol clamp method, in which alcohol is administered intravenously, allowing study participants to achieve and maintain a target breath alcohol concentration (BrAC) for an extended period of time. This tool minimizes the variability in BrACs that occurs after alcohol consumption by administering alcohol at a dose and rate that is computed for each person individually. The alcohol clamp can be used to evaluate several influences on alcohol elimination, including gender, ethnicity, genetic variations in alcohol-metabolizing enzymes, and food consumption.

Language: en

LA - en SN - 1535-7414 UR - http://dx.doi.org/ ID - ref1 ER -