TY  - JOUR
PY  - 2001//
TI  - Psychoactive drug use in a declared non-addicted control sample and comorbidity. Results of a study in 860 French-speaking subjects
JO  - Annales de Médecine Interne (Paris)
A1  - Nezelof, S.
A1  - Taccoen, Y.
A1  - Corcos, M.
A1  - Girardon, N.
A1  - Perez-Diaz, F.
A1  - Bizouard, P.
A1  - Venisse, J. L.
A1  - Halfon, Olivier
A1  - Loas, G.
A1  - Lang, F.
A1  - Flament, M.
A1  - Jeammet, P.
SP  - IS18
EP  - 25
VL  - 152
IS  - Suppl 3
N2  - AIMS: This study, conducted within the framework of a broader research program of the INSERM 494013 Dependence Network, was designed to estimate illicit drug use and tobacco smoking in a declared non-addicted sample and to determine whether illicit drug users differ from non-users in terms of comorbidity. METHODS: The study was conducted in an "all and sundry" sample of subjects. Patterns of drug use and comorbid factors (psychiatric disorders, suicide attempts, repeated accidents, social inadaptation) were assessed using a semi-structured interview (heteroevaluation, MINI DSM IV interview, Gröningen). RESULTS: Among 860 subjects, 107 (12.4%) used illicit drugs and 26 of these 107 (24.3%) were dependent users or abusers. Specific analysis of non-dependent non-abuser subjects who had used illicit drugs (70 occasional and 11 regular users) showed a higher rate of use in younger subjects (12.7% in the 15-24 year group, 5.7% in the 24-49 year group) and men. Except for repeated accidents (OR=5.5 [1.6-18.5]), comorbid disorders were not more frequent in non-users than in users. CONCLUSION: Besides use for recreational purposes, the rate of use of illicit drugs with abuse or dependence was high in our non-clinical sample. Although no specific comorbid psychiatric disorders were identified among non-dependent non-abuser subjects who had used illicit drugs, the frequency of repeated accidents evidenced the ill-fated side effects of illicit drugs and/or the specific biopsychological vulnerability of these subjects. This highlights the importance of not neglecting drug abuse.<p /> <p>Language: fr</p>
LA  - fr
SN  - 0003-410X
UR  - http://dx.doi.org/
ID  - ref1
ER  -