TY  - JOUR
PY  - 2003//
TI  - Isotretinoin and psychiatric illness in adolescents and young adults
JO  - Annals of pharmacotherapy
A1  - Enders, Shelly J.
A1  - Enders, Jason M.
SP  - 1124
EP  - 1127
VL  - 37
IS  - 7-8
N2  - OBJECTIVE: To evaluate the relationship between isotretinoin and psychiatric illness in adolescents and young adults. DATA SOURCES: Primary literature located via MEDLINE (1966-December 2002). Key terms were isotretinoin, depression, psychosis, suicide, and adolescents. DATA SYNTHESIS: Information regarding depression was added to isotretinoin labeling in 1998 following a series of case reports and submitted to the MedWatch system. CONCLUSIONS: Although a causal relationship may exist between isotretinoin and psychiatric illness in adolescents and young adults, this has not been demonstrated in the literature. Until evidence establishes a presence or lack of causality, prescribers should exercise caution when treating adolescents and young adults with isotretinoin.<p /> <p>Language: en</p>
LA  - en
SN  - 1060-0280
UR  - http://dx.doi.org/
ID  - ref1
ER  -