TY - JOUR PY - 2009// TI - Antidepressant use in children and adolescents JO - Archives de Pediatrie A1 - Bailly, D. SP - 1415 EP - 1418 VL - 16 IS - 10 N2 - Relative to placebo, selective serotonin reuptake inhibitors (SSRI) are efficacious for paediatric affective disorders, although their clinical effects appear relatively modest in major depressive disorder, intermediate in obsessive-compulsive disorder, and stronger in anxiety disorders. If SSRIs modestly increase the risk of occurrence of suicidal ideation and behavior, several studies show that their use is associated with a significant decrease in the suicide rates in children and adolescents, probably because of their efficacy, compliance, and low toxicity in overdose.
Language: fr
LA - fr SN - 0929-693X UR - http://dx.doi.org/10.1016/j.arcped.2009.03.017 ID - ref1 ER -