TY - JOUR PY - 1993// TI - Three-year follow-up of patients with panic disorder after short-term treatment with alprazolam and imipramine JO - International clinical psychopharmacology A1 - Lepola, U. M. A1 - Rimón, R. H. A1 - Riekkinen, P. J. SP - 115 EP - 118 VL - 8 IS - 2 N2 - Fifty-five patients with moderate to sever panic disorder were treated for 9 weeks with alprazolam or imipramine and were then, except for one patient who had committed suicide, re-examined after on average 3 years of treatment. At follow-up most patients (74%) did not suffer from panic attacks at all. In the beginning of the study 87% exhibited phobic avoidance behaviour but after 3 years 68% no longer revealed phobic behaviour. At follow-up 28% of the patients were no longer having psychotropic drug treatment and 20% were completely free of overt psychopathology. No tolerance phenomena were associated with the long-term medication applied in the study.

Language: en

LA - en SN - 0268-1315 UR - http://dx.doi.org/ ID - ref1 ER -