TY - JOUR PY - 2007// TI - An open-label study to evaluate the transition of patients with chronic plaque psoriasis from cyclosporine to alefacept JO - Journal of drugs in dermatology A1 - Magliocco, Melissa A. A1 - Lozano, Ann Marie A1 - Van Saders, Claudia A1 - Schuler, Kristine W. A1 - Gottlieb, Alice B. SP - 424 EP - 427 VL - 6 IS - 4 N2 - Eleven patients with well-controlled psoriasis on cyclosporine (Physician's Global Assessment [PGA] of "mild" or better) participated in an open-label study that evaluated a strategy for transition to alefacept. Using this transition strategy, 7 of 11 patients (64%) maintained PGA scores. Quality of life improved or was maintained in all patients. Adverse events and reductions in CD4+ T cell counts were consistent with those seen during alefacept monotherapy.

Language: en

LA - en SN - 1545-9616 UR - http://dx.doi.org/ ID - ref1 ER -