TY - JOUR PY - 1996// TI - Suicidal chloroquine poisoning: clinical course, autopsy findings, and chemical analysis JO - Journal of forensic sciences A1 - Muhm, M. A1 - Stimpfl, T. A1 - Malzer, R. A1 - Mortinger, H. A1 - Binder, Renée L. A1 - Vycudilik, W. A1 - Berzlanovich, A. A1 - Bauer, G. A1 - Laggner, A. N. SP - 1077 EP - 1079 VL - 41 IS - 6 N2 - Suicidal overdose of chloroquine is rare. We present a 14-year-old girl who was admitted to our Emergency Department after intentional ingestion of 7.5 g of chloroquine base followed by cardiac and respiratory arrest. Despite early mechanical ventilation, cardiac support, and treatment with high doses of diazepam, the patient died. Laboratory investigation indicated disseminated intravascular coagulation confirmed by petechial hemorrhages in the leptomeninges at autopsy, a finding that has not previously been described. Postmortem tissue analysis demonstrated early drug distribution to the medulla oblongata and cerebellum.
Language: en
LA - en SN - 0022-1198 UR - http://dx.doi.org/ ID - ref1 ER -