TY  - JOUR
PY  - 1996//
TI  - Multidrug-resistant tuberculosis: response to treatment
JO  - Journal of the Medical Association of Thailand
A1  - Saenghirunvattana, S.
A1  - Charoenpan, P.
A1  - Vathesatogkit, P.
A1  - Kiatboonsri, S.
A1  - Aeursudkij, B.
SP  - 601
EP  - 603
VL  - 79
IS  - 9
N2  - OBJECTIVE: We investigated clinical response and mortality rates in 18 HIV- negative patients with multidrug-resistant tuberculosis. METHOD: We obtained detailed data from our hospital on patients with multidrug - resistant tuberculosis defined as tuberculosis resistant at least to isoniazid and rifampicin. Therapeutic responses were evaluated by both microbiologic and clinical data. RESULTS: From January 1985 to December 1990, 18 HIV-negative patients were identified and treated. One patient committed suicide 1 week after receiving antituberculous drugs. Of the 17 patients, 10 (58.8%) had clinical response as well as microbiologic response, 6 (35.3%) were persisters during 24 months of follow-up, and 1 (5.8%) died after 30 months of treatment. The median follow-up for the patients was 87 weeks (range, 24 to 212). For those who responded well, there was no relapse.<p /> <p>Language: en</p>
LA  - en
SN  - 0125-2208
UR  - http://dx.doi.org/
ID  - ref1
ER  -