TY  - JOUR
PY  - 1998//
TI  - Azathioprine ingestion with suicidal intent by an adolescent with chronic juvenile polyarthritis
JO  - Klinische padiatrie
A1  - Krüger, C.
A1  - Jüngert, J.
A1  - Schmitt-Grohe, S.
A1  - Beese, M.
A1  - Ruder, H.
SP  - 136
EP  - 138
VL  - 210
IS  - 3
N2  - We report on a 13 years 7 months old boy who ingested 650 mg azathioprine in a suicide attempt. His baseline medication was azathioprine and methotrexate for control of juvenile chronic polyarthritis. After the induction of vomiting by ipecacuanha sirup and administration of charcoal (1 g/kg), he was closely followed for haematological, hepatic, and renal side effects. During the following days, no serious adverse events were noted except that the thrombocyte (from 403,000 down to 199,000/microliter) and total leukocyte count decreased moderately (from 12,000 down to 7100/microliter). On the basis of this case report and the available literature, the potential acute toxicity of azathioprine and possible treatment modalities are discussed.<p /> <p>Language: de</p>
LA  - de
SN  - 0300-8630
UR  - http://dx.doi.org/10.1055/s-2008-1043866
ID  - ref1
ER  -