TY  - JOUR
PY  - 1981//
TI  - An analytical model describing the exchange processes of alcohol in the respiratory system
JO  - Proceedings International Council on Alcohol, Drugs and Traffic Safety Conference
A1  - Slemeyer, A.
SP  - 456
EP  - 468
VL  - 1981
IS  - 
N2  - The diffusion processes of ethanol in the respiratory system are analyzed and simulated in a model consisting of 3-compartments with lumped parameters. The areas of exchange are differentiated into the alveolar space, the upper respiratory tract and the mouth-throat cavity. The underlying processes such as diffusion through membranes, air mixing and convection of ethanol gas are approximated by numerical equations processed through a digital computer using the ventilation as loop controlling variable. The parameters of the model were optimized by direct comparison of its behaviour with measured time courses of alcohol concentration obtained in drinking experiments. From these data "standard parameters" were derived and used for studying the influence of ventilation on the breath alcohol concentration. In this way it can be shown that the micin layer on the respiratory duct is heavily involved in ethanol-exchange during respiration. (TRRL)<p /> 
LA  - 
SN  - 
UR  - http://dx.doi.org/
ID  - ref1
ER  -