TY  - JOUR
PY  - 2000//
TI  - An intersubstance approach to drug-concentration-drug effect correlation via metaanalytic data of experimental studies
JO  - Proceedings International Council on Alcohol, Drugs and Traffic Safety Conference
A1  - Berghaus, G.
A1  - Grab, H.
A1  - Sticht, G.
SP  - 
EP  - p.
VL  - 2000
IS  - 
N2  - Based on a metaanalytical analysis of experimental studies combined with pharmacokinetic data we tried to correlate the time of worst human performance and the time of highest serum-concentration after oral application of several drugs. Critically discussed we can postulate - as a first result - that the dosage does not influence the time of highest concentration but the time of worst performance, and that for substances with short resorption times the maximum of performance decrements is situated after the maximum of concentration and vice versa.<p /> 
LA  - 
SN  - 
UR  - http://dx.doi.org/
ID  - ref1
ER  -