TY - JOUR PY - 1981// TI - Driving performance of patients receiving diazepam medication JO - Proceedings International Council on Alcohol, Drugs and Traffic Safety Conference A1 - De Gier, Johan J. A1 - Nelemans, F.a. SP - 1009 EP - 1023 VL - 1981 IS - N2 - The primary goal of this study was to compare a specific task-performance in a laboratory test and real driving performance of ambulant patients using diazepam medication with those of controls. Plasma and saliva samples were taken to investigate a level-response relationship. Measurement of real driving performance was based on the method described by De Gier (1979). The design of the laboratory test was based on a vigilance task (high-attention demanding task) directly followed by a simple eye-hand coordination task (low-attention demanding task). Twenty two males participated in the study. Diazepam was given orally on prescription, mostly on a maintenance dose of three times a day 5 mg. Diazepam was found to affect real driving performance and the low-attention-demanding task performance. The results indicated that there is no relationship between plasma or saliva levels of diazepam and/or its major metabolite n-desmethyldiazepam and real driving performance and/or laboratory task performance. (Author/TRRL)
LA - SN - UR - http://dx.doi.org/ ID - ref1 ER -