TY  - JOUR
PY  - 2011//
TI  - Experimental trauma models: an update
JO  - Journal of biomedicine and biotechnology
A1  - Frink, Michael
A1  - Andruszkow, Hagen
A1  - Zeckey, Christian
A1  - Krettek, Christian
A1  - Hildebrand, Frank
SP  - 797383
EP  - 797383
VL  - 2011
IS  - online
N2  - Treatment of polytrauma patients remains a medical as well as socioeconomic challenge. Although diagnostics and therapy improved during the last decades, multiple injuries are still the major cause of fatalities in patients below 45 years of age. Organ dysfunction and organ failure are major complications in patients with major injuries and contribute to mortality during the clinical course. Profound understanding of the systemic pathophysiological response is crucial for innovative therapeutic approaches. Therefore, experimental studies in various animal models are necessary. This review is aimed at providing detailed information of common trauma models in small as well as in large animals.<p />  <p>Language: en</p>
LA  - en
SN  - 1110-7243
UR  - http://dx.doi.org/10.1155/2011/797383
ID  - ref1
ER  -