TY - JOUR PY - 2002// TI - Death in epilepsy with special attention to suicide cases JO - Epilepsy research A1 - Fukuchi, Toshihiko A1 - Kanemoto, Kousuke A1 - Kato, Masaaki A1 - Ishida, Shirou A1 - Yuasa, Shoji A1 - Kawasaki, Jun A1 - Suzuki, Shigeru A1 - Onuma, Teiichi SP - 233 EP - 236 VL - 51 IS - 3 N2 - To examine clinical features of cases of death among epilepsy patients as a case-control study, with special attention to suicide, we analyzed the records of 43 deceased patients with well-classified epilepsy. The subjects were compared with 1,722 control patients who showed definite subtypes of epilepsy. As a result, among the major causes of death, 13 of the subjects suffered accidents (mostly drowning), ten experienced sudden unexpected death, seven had status epilepticus, and six committed suicide. There were no significant differences with regard to clinical variables except for psychotic episodes, which were more frequently encountered in subjects than in controls (chi(2)=6.771, P=0.009, Yates' modification). Statistically significant differences were found by epilepsy type as well (chi(2)=14.72, P=0.002), with temporal lobe epilepsy (TLE) proving to be most closely associated with death among the epilepsy patients. Further, suicide was only encountered in patients with TLE and the association was statistically significant (chi(2)=5.119, P=0.024). Half of those who committed suicide (n=3), did so by jumping in front of an oncoming train while in the midst of an episode of postictal psychosis. In conclusion, most cases of suicide in patients with epilepsy were found to be the result of an immediate causal relationship with ictal or interictal epileptic manifestations, rather than a result of augmentation of psychosocial stressors generated by a long-standing handicap derived from the severe illness.
Language: en
LA - en SN - 0920-1211 UR - http://dx.doi.org/ ID - ref1 ER -