TY - JOUR PY - 2006// TI - Evaluation of post-mortem ethanol concentrations in pericardial fluid and bone marrow aspirate JO - Forensic science international A1 - Maeda, Hitoshi A1 - Zhu, Bao-Li A1 - Ishikawa, Takaki A1 - Oritani, Shigeki A1 - Michiue, Tomomi A1 - Li, Dong-Ri A1 - Zhao, Dong A1 - Ogawa, Masafumi SP - 141 EP - 143 VL - 161 IS - 2-3 N2 - This study confirmed post-mortem ethanol concentrations in pericardial fluid and bone marrow aspirate in comparison with those in the blood in medicolegal autopsy cases (n = 140, within 48 h post-mortem). The specimens were examined by head-space gas chromatography/mass spectrometry. Ethanol concentrations in the pericardial fluid (y) were approximately equivalent to those in peripheral blood (x): y = 0.99x + 0.02, n = 44, r = 0.972. A high stomach ethanol concentration (>10 mg/ml) appeared to mildly affect the pericardial levels. There was no significant interference in drowning cases. Ethanol concentrations in bone marrow aspirates (y) also showed a good correlation with those in the peripheral blood (x): y = 0.77 x + 0.02, n = 20, r = 0.981. A dissociation was observed in cases of delayed death from hemorrhagic/traumatic shock and elderly victims. These findings suggest that pericardial fluid and bone marrow aspirate can be used as an alternative material when adequate blood specimens are not available.
Language: en
LA - en SN - 0379-0738 UR - http://dx.doi.org/10.1016/j.forsciint.2006.01.016 ID - ref1 ER -