TY - JOUR PY - 1995// TI - Increased aggressive responding in male volunteers following the administration of gradually increasing doses of testosterone cypionate JO - Drug and alcohol dependence A1 - Kouri, E. M. A1 - Lukas, Scott E. A1 - Pope, H. G. A1 - Oliva, P. S. SP - 73 EP - 79 VL - 40 IS - 1 N2 - The present study assessed the effects of supraphysiologic doses of testosterone on aggressive responding in a controlled laboratory setting. Eight male subjects received gradually increasing doses of testosterone cypionate (150 mg/week for two weeks, 300 mg/week for two weeks, and 600 mg/week for two weeks) or placebo using a double-blind, randomized, cross-over design. Subjects were tested both before and after the series of injections. During the experimental session subjects could press a button to accumulate points exchangeable for money (non-aggressive response) or press another button to subtract points from a fictitious opponent (aggressive response). Aggressive responding was instigated by subtracting points from the subject which was attributable to the fictitious opponent. Testosterone administration resulted in a significantly higher number of aggressive responding compared to placebo.
Language: en
LA - en SN - 0376-8716 UR - http://dx.doi.org/ ID - ref1 ER -