TY - JOUR PY - 1997// TI - Prior brain injury protects death from local anaesthetic-induced convulsion JO - Brain research A1 - Endoh, H. A1 - Kumagai, Y. A1 - Baba, H. A1 - Yamakura, T. A1 - Taga, K. A1 - Sato, K. A1 - Fukuda, S. A1 - Shimoji, K. SP - 136 EP - 139 VL - 767 IS - 1 N2 - Minor brain injury was inflicted with a small hypodermic needle at four sites from the scalp 7 days before the production of convulsion by i.p. injection of 100 mg/kg lidocaine in mice. The latency to convulsion and survival rate were significantly longer and higher, respectively, in the brain-injured group than in the sham-operated one. Thus, the results suggest that a protective mechanism develops in the injured brain against asphyxia caused by lidocaine convulsion.
Language: en
LA - en SN - 0006-8993 UR - http://dx.doi.org/ ID - ref1 ER -